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The Anaplasma platys (qPCR) product is used to detect sequences characteristic of the Anaplasma platys bacterium in DNA preparations obtained from the blood of dogs and other animals, as well as in DNA preparations obtained from ticks.
Kit size: 100 reactions
Reaction: duplex (FAM: Anaplasma platys, HEX: internal control)
Internal control: exogenous/endogenous
Determination: qualitative/quantitative
Kit components:
Anaplasma platys is an obligate intracellular Gram-negative bacterium that infects platelets in dogs. This bacterium was once classified as belonging to the genus Ehrlichia, but was reclassified based on phylogenetic analysis of the 16S ribosomal DNA (rDNA) gene. Infection with A. platys in dogs causes thrombocytotropic anaplasmosis (TA, Infectious Canine Cyclic Thrombocytopenia, ICCT) in dogs.
TA is an infectious disease transmitted by ticks. A characteristic feature of this disease is cyclical thrombocytopenia (low platelet count). Other possible symptoms of the disease include apathy, loss of appetite, fever, and pale mucous membranes. In acute cases, vomiting, diarrhea, and enlargement of the lymph nodes, liver, and spleen may also occur. Anaplasmosis can also take a chronic form.
Although this pathogen is important for small animal clinics, A. platys has a wide range of hosts, including cats, cows, camels, etc. Isolated cases of human infection have been reported. Anaplasma platys is found in various regions of the world, including Asia, Europe, Africa, and America.
A. platys occurs mainly in Mediterranean countries. Animals become infected through tick bites. This bacterium has been found in ticks of the species Rhipicephalus sanguineus, Dermacentor auratus, and Ioxides persulcatus. Humans can also become infected in other ways, e.g., through blood transfusions.
The mainstay of treatment for canine anaplasmosis is long-term antibiotic therapy, most often based on tetracyclines, or doxycycline in the case of thrombocytic anaplasmosis. Supportive medications and symptomatic treatment are also used, depending on the animal’s condition. Occasionally, glucocorticoids or blood transfusions may be necessary, especially in cases of severe anemia and thrombocytopenia.
