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The Ascaris lumbricoides hominis (qPCR) product is used to detect sequences specific to the human roundworm Ascaris lumbricoides hominis in DNA preparations obtained from human feces.
Kit size: 100 reactions
Reaction: duplex (FAM: Ascaris lumbricoides hominis, HEX: internal control)
Internal control: exogenous/endogenous
Determination: qualitative/quantitative
Kit components:
The human roundworm A. lumbricoides is one of the most common parasites in the world, infecting 1.2 billion people worldwide. Infections are most commonly documented in sub-Saharan Africa, the Americas, China, and East Asia. The course of infection with serious health consequences is observed in 122 million cases annually. However, ascariasis is still considered a neglected tropical disease.
The spectrum of diseases associated with human roundworm infection is known as ascariasis. Morbidity and mortality increase when carrying worms, and individuals who are carriers of mild infections tend to be asymptomatic. Relatively few people carry enough worms to cause serious or life-threatening disease.
Most cases of infection caused by Ascaris lumbricoides affect school-age children. This is due to the increased risk of infection associated with age, as well as the narrower intestinal lumen. It is estimated that symptoms are observed in 8-15% of people infected with human roundworm. The symptoms of ascariasis can generally be divided into acute and chronic.
People infected with A. lumbricoides tend to experience acute pneumonia, difficulty breathing, and fever as a result of larval migration through the lung tissue. Abdominal bloating and pain, nausea, and diarrhea are also characteristic symptoms of adult worm infection and chronic ascariasis. Occasionally, entangled adult may cause mechanical intestinal obstruction, with frequency of 0.005–2 cases per 1,000 infections per year. There is also an association between roundworm infection and cognitive decline in humans.
