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The Ascaris & Trichuris (qPCR) product is used to detect sequences specific to parasites of the genera Ascaris and Trichuris in DNA preparations obtained from human feces.
Kit size: 100 reactions
Reaction: triplex (FAM: Ascaris, HEX: internal control, Texas Red: Trichuris)
Internal control: exogenous/endogenous
Determination: qualitative/quantitative
Kit components:
The human roundworm Ascaris lumbricoides is one of the most common parasites in the world, infecting 1.2 billion people worldwide. Infections are most commonly documented in sub-Saharan Africa, the Americas, China, and East Asia. The course of infection with serious health consequences is observed in 122 million cases annually.
The spectrum of diseases associated with A. lumbricoides infection is known as ascariasis. Relatively few people carry enough worms to cause life-threatening or severe morbidity. Most cases of illness caused by A. lumbricoides occur in school-aged children. This is due to the increased risk of infection associated with age, as well as the narrower intestinal lumen.
People infected with A. lumbricoides tend to experience acute pneumonia, difficulty breathing, and fever as a result of larvae migrating through lung tissue. Abdominal bloating and pain, nausea, and diarrhea are also characteristic symptoms of adult worm infection and chronic ascariasis.
T. trichiura infections affect approximately 464 million people worldwide. In less developed communities, the prevalence of Trichuris infection can exceed 90%, with school-aged children having the highest parasite burden. 144 million preschool children and 233 million school-aged children are infected with T. trichiura.
People become infected by consuming contaminated food or water containing whipworm eggs. The larvae hatch in the small intestine and migrate to the large intestine, where they develop into adult worms. The global burden of Trichuris infection is associated with high infection intensity, as mild infections are often asymptomatic or subclinical. Symptoms include abdominal discomfort, pain, bloody diarrhea, anemia, malnutrition, weight loss, and in severe cases, complications such as obstruction and perforation of the large intestine.
Heavy parasite infestation in children can lead to Trichuris Dysentery Syndrome (TDS), characterized by anemia, stunted growth, and impaired cognitive function.
