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The Aspergillus (qPCR) product is used to detect sequences specific to fungal species of the genus Aspergillus in DNA preparations obtained from environmental samples and biological material collected from humans and animals.
Kit size: 100 reactions
Reaction: duplex (FAM: selected species of Aspergillus, HEX: internal control)
Internal control: exogenous/endogenous
Determination: qualitative/quantitative
Kit components:
Species of the genus Aspergillus are microscopic fungi commonly found throughout the world. They are found in water, soil, vegetation, fruit, food, homes, and the air. Most species of Aspergillus are saprophytes. A few species are parasites. The importance of Aspergillus species in industry, science, and medicine/veterinary medicine is quite broad. Some species cause plant rot (e.g., A. niger). A number of species are used in industry and science. Some species of Aspergillus cause disease (aspergillosis) in animals and humans, and also produce mycotoxins.
The genus Aspergillus is also one of the most common types of mold found in human indoor environments. Exposure to mold can cause allergic reactions in people who are sensitive to fungi. Such people account for about 10% of the total population and 40% of asthmatics. Aspergillus is a particularly harmful type of mold comprising several species that are opportunistic pathogens capable of infecting people with compromised immune systems.
Aspergillus species play a role in three different clinical situations in humans: opportunistic infections, allergic conditions, and poisoning, with inhalation being the primary route of transmission of spores. Aspergillus species have been linked to a number of infections, including allergic bronchopulmonary aspergillosis (ABPA), aspergilloma, chronic necrotizing aspergillosis (CNA), and invasive pulmonary aspergillosis (IPA), collectively referred to as aspergillosis. The disease usually affects the lungs and can also spread to other parts of the body.
Aspergillosis primarily affects people with existing medical conditions, especially those with damaged lungs and compromised immune systems. Typical symptoms associated with aspergillosis include difficulty breathing, increased thirst, diarrhea, and fever. Of all the species belonging to the genus Aspergillus, A. niger, A. flavus, A. fumigatus, A. versicolor, A. nidulans, and A. candidus are the most significant in the development of human disease.
