Log in to see the prices.
The price above is a net price.
The FCoV (qPCR) product is used to detect sequences specific to feline coronavirus (FCoV) in RNA preparations obtained from cat feces, tissues, or fluids (e.g., exudate).
Kit size: 100 reactions
Reaction: duplex (FAM: FCoV, HEX: internal control)
Internal control: exogenous/endogenous
Determination: qualitative/quantitative
Kit components:
FCoV (feline coronavirus) belongs to the genus alphacoronaviruses. It has a single-stranded RNA genome, a phospholipid envelope, and a characteristic crown on its surface formed by S proteins. Coronavirus genomes are relatively large, ranging in size from 26,400 to 31,700 nucleotides. There are two forms of the feline coronavirus. One form is feline enteric coronavirus (FECV). This form is common in cats and causes no symptoms or only temporary diarrhea.
The second form is a particularly virulent virus called feline infectious peritonitis virus (FIPV). This form of coronavirus occurs in a few percent of cats (especially young ones) as a result of FECV mutation. FIPV causes a severe disease known as feline infectious peritonitis (FIP) with a poor prognosis, leading to inflammation of the serous membranes and the formation of characteristic granulomatous lesions in the internal organs. FIP often presents with nonspecific symptoms, making it difficult to diagnose with certainty. Differential diagnosis is usually required.
Mutations within the S gene encoding the spike protein cause the FECV virus to transform into FIPV. As a result of these mutations, FCoV acquires tropism for macrophages, while losing its intestinal tropism.
According to studies, over 90% of tested breeder cats tested positive for coronavirus. It is less common in feral cats. However, the FIP mutation itself is not very contagious, as cats with the virus can only infect a healthy cat through blood contact. Therefore, it’s important to remember that FIP most often occurs as a mutation of the FECV strain and affects approximately 5% of cats with FECV.
