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The FeLV RNA (qPCR) product is used to detect sequences specific to feline leukemia virus (FeLV) in RNA preparations obtained from biological material collected from cats.
Kit size: 100 reactions
Reaction: duplex (FAM: FeLV, HEX: internal control)
Internal control: exogenous/endogenous
Determination: qualitative/quantitative
Kit components:
FeLV (Feline Leukemia Virus) is a retrovirus of the genus Gammaretrovirus, responsible for one of the most common and serious infectious diseases in cats. The virus infects several percent of domestic cats (up to 8.8% in Europe) and some species of wild cats, such as the Iberian lynx. Disease caused by Feline Leukemia Virus significantly affects the length and quality of life of animals, leading to a number of symptoms. The most common are weakness, loss of appetite, anemia, gum inflammation, impaired immunity, and eventually cancer and death.
The virus is mainly transmitted through contact with secretions from infected cats—saliva, urine, feces, and blood—making infection particularly risky in environments where cats live in close contact. There are several subtypes of feline leukemia virus:
In some cats, after infection, the virus does not develop progressively, but remains in the body in a latent form – this is known as a regressive infection.
In terms of structure, feline leukemia virus is a single-stranded RNA virus (+ssRNA-RT) which, during its life cycle, converts its genetic material into double-stranded DNA (provirus stage) and integrates into the host cell genome. Its genome contains three main genes: gag (encoding capsid proteins), pol (encoding enzymes necessary for replication, including reverse transcriptase), and env (responsible for viral envelope glycoproteins).
Early detection of feline leukemia virus is crucial for monitoring the animal’s health, making treatment decisions, and protecting other cats from infection. Although there is no causal treatment to eliminate the virus, proper veterinary care and prevention, including vaccination, can significantly prolong the life of infected cats and limit the spread of infection.
