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The FHV-1 (qPCR) product is used to detect sequences specific to feline herpesvirus type 1 (FHV-1) in DNA preparations obtained from biological material collected from cats.
Kit size: 100 reactions
Reaction: duplex (FAM: FHV-1, HEX: internal control)
Internal control: exogenous/endogenous
Determination: qualitative/quantitative
Kit components:
Feline herpesvirus type 1 (FHV-1, Feline Herpesvirus 1) is a double-stranded, enveloped DNA virus belonging to the α-herpesvirinae subtype of the Herpesviridae family. This subtype is widespread throughout the world. FHV-1 is a highly contagious pathogen of domestic cats and other members of the cat family (Felidae), including South Chinese tigers and cheetahs.
Young and adolescent cats are at risk of acute primary disease, and most of them develop a persistent infection. About half of persistently infected cats shed the virus throughout their lives. These carriers can spread the infection to other individuals, making disease prevention and control difficult. Kittens aged 2–3 months are particularly vulnerable to infection. When kittens become infected with this virus, secondary infections are likely to occur due to the weak immunity induced by FHV-1. The final mortality rate among infected animals can reach 70%.
Typical symptoms of upper respiratory tract infection in cats include neutrophilic rhinitis with intranuclear eosinophilic inclusion bodies. These symptoms usually resolve within 7–14 days. However, the virus can remain in the cat’s body in a latent form and reactivate under stressful conditions. FHV-1 can also infect the cornea, causing ulcerative keratitis. It is the most common cause of keratitis and corneal ulcers in cats and so-called gummy eyes in kittens. Kittens under three months of age and older animals in stressful situations are particularly susceptible to infection.
After the clinical signs of the acute phase of infection subside, a significant fraction of animals remain asymptomatic carriers or develop latent infection. Only in a small number of animals (20%) is the virus completely eliminated.
