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The Helicobacter spp. (qPCR) product is used to detect sequences specific to bacteria of the genus Helicobacter in DNA preparations obtained from feces and biopsies of the gastrointestinal mucosa taken from animals and humans.
Kit size: 100 reactions
Reaction: duplex (FAM: Helicobacter spp., HEX: internal control)
Internal control: exogenous/endogenous
Determination: qualitative/quantitative
Kit components:
The genus Helicobacter includes gram-negative, spiral-shaped bacteria that commonly colonize the human stomach and the gastrointestinal tract of animals. The most common species of Helicobacter in humans is H. pylori, with a prevalence of approximately 50%. Two other known human species of this genus that inhabit the stomach are H. heilmannii and H. felis. H. bilis, H. rappini, and H. pullorum have been detected in the human biliary tree and are thought to play a role in liver disease. In addition, H. cinaedi, H. canis, H. pullorum, H. fennelliae, H. canadensis, H. rappini, and H. winghamensis have been cultured from human fecal samples.
Helicobacter bacteria are also commonly found in the digestive systems of animals. H. bilis, H. hepaticus, and H. muridarum are commonly found in the intestines of small rodents. In chickens and other birds, the species H. pullorum and H. pametensis are found. Most Helicobacter infections of the gastric mucosa in dogs and cats are mixed infections caused by various species, including H. felis, H. bizzozeronii, and H. salomonis. In dogs, H. canis is also present. In pigs, H. suis is present.
Helicobacter pylori is an etiological factor in chronic gastritis, gastric ulcer disease, gastric cancer, and MALT lymphoma in humans. The consequences of Helicobacter infection in animals are much less well understood. It is known that infection with these bacteria can cause symptoms such as: The symptoms in a dog infected with these bacteria are quite noticeable and require diagnosis and treatment by a veterinarian. They include dehydration, vomiting, loss of appetite, abdominal pain, weight loss, diarrhea, weakness, and malaise.
