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The Mycoplasma haemocanis, haematoparvum (qPCR) product is used to detect sequences specific to the hemotropic mycoplasmas Mycoplasma haemocanis and Candidatus Mycoplasma haematoparvum in DNA preparations obtained from dog blood.
Kit size: 100 reactions
Reaction: triplex (FAM: Mycoplasma haemocanis, Texas Red: Candidatus Mycoplasma haematoparvum, HEX: internal control)
Internal control: exogenous/endogenous
Determination: qualitative/quantitative
Kit components:
Mycoplasma haemocanis and Candidatus Mycoplasma haematoparvum are Gram-negative parasitic bacteria that infect dogs and cause infectious anemia. Both species belong to the hemotropic mycoplasmas (hemoplasmas).
Mycoplasma haemocanis and Candidatus M. haematoparvum are the most commonly diagnosed species of canine hemoplasma. Both species are found worldwide. These bacteria are most often the cause of varying degrees of hemolytic anemia, but they can also cause fever, apathy, adenopathy, lack of coordination, splenomegaly, anorexia, lethargy, jaundice, dehydration, weight loss, and sudden death. Although hemoplasma infections are usually species-specific, in addition to Mycoplasma haemocanis and Candidatus M. haematoparvum, M. ovis, M. suis, Candidatus Mycoplasma haemobos, Candidatus Mycoplasma haemominutum, and Candidatus Mycoplasma turicensis are also occasionally detected in dogs. Importantly, infections with Candidatus M. haematoparvum, M. ovis, and M. suis have also been described in humans.
Dogs that have undergone splenectomy are particularly susceptible to developing anemia as a result of infection with M. haemocanis. Additional factors contributing to the development of the disease include immunodeficiency, parvovirus infection, lymphosarcoma, or bacterial infection. Symptoms of infection include episodes of severe anemia and bleeding disorders in dogs, but the course of the disease may not be clinically obvious.
The routes of transmission of hemoplasmas in dogs are not fully understood. Blood-sucking arthropods, such as fleas and ticks, probably act as vectors for the disease. In addition, it has been suggested that infections may occur during animal fights, intrauterine transfer, and transmission through lactation and blood transfusions from apparently healthy carrier dogs.
