Log in to see the prices.
The price above is a net price.
The Periodontal Disease Panel II (qPCR) product is used to detect sequences specific to eight pathogens causing periodontal disease in DNA preparations obtained from material collected from the human oral cavity.
Kit size: 100 markers
Reaction_1: triplex (FAM: Aggregatibacter actionomycetemcomitans, HEX: internal control, Texas Red: Porphyromonas gingivalis)
Reaction_2: triplex (FAM: Treponema denticola, HEX: internal control, Texas Red: Tannerella forsythia)
Reaction_3: triplex (FAM: Prevotella intermedia, HEX: internal control, Texas Red: Parvimonas micra)
Reaction_4: triplex (FAM: Fusobacterium nucleatum, HEX: internal control, Texas Red: Eubacterium nodatum)
Internal control: exogenous/endogenous
Determination: qualitative/quantitative
Kit components:
Periodontal disease, also known as gum disease, is a series of pathological processes affecting the periodontium. This term covers the gingival tissue, alveolar bone, cementum, and periodontal ligament. According to the latest classification, periodontal diseases are divided into three categories:
The mildest form of periodontal disease is gingivitis, which can occur in up to 90% of the population. Gingivitis is caused by the accumulation of bacteria and debris between the gum line and the tooth. This accumulation is also referred to as plaque.
The development of gum disease is promoted by several patient-specific risk factors and inadequate oral hygiene. In the case of inadequate oral hygiene, anaerobic organisms responsible for the progression of the disease colonize deeper areas of the periodontium, causing its gradual destruction. Several species of bacteria have been linked to periodontal disease. The most important of these are Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia. Risk factors contributing to the development of the disease include smoking, diabetes, pregnancy, age, and certain genetic disorders.
The Periodontal Disease Panel II (qPCR) product allows for the detection of eight species of bacteria involved in the development of gum disease:
The above bacteria can be detected both qualitatively and quantitatively. Quantitative detection is possible thanks to the included set of calibrators, which allow a three-point calibration curve to be constructed. The bacteria are detected in four triplex reactions. Each reaction is used to detect two species of bacteria and an exogenous internal control.
