Description
The Schistosoma haematobium (qPCR) product is used to detect sequences specific to the Schistosoma haematobium fluke in DNA preparations obtained from human urine and blood.
Product characteristics
Kit size: 100 reactions
Reaction: duplex (FAM: Schistosoma haematobium, HEX: internal control)
Internal control: exogenous/endogenous
Determination: qualitative/quantitative
Kit components:
- Reaction mixture: contains DNA polymerase, probes and primers, and other qPCR reaction components;
- Positive control;
- Negative control;
- PCR-grade water;
- Internal control
Description of the Schistosoma haematobium fluke
The blood fluke Schistosoma haematobium is a species of flatworm whose definitive host is usually humans. It causes a disease called schistosomiasis. The adult form of the flatworm lives in blood vessels and feeds on blood. The intermediate hosts of blood flukes are freshwater snails, mainly from the Bulinidae family. Blood flukes can live up to 18 years in the human body.
Schistosoma haematobium is one of three main species of schistosomes that infect humans. The other two species are Schistosoma mansoni and Schistosoma japonicum. All three species are found in different (sub)tropical areas. S. mansoni is common in many countries in Africa, parts of the Middle East, South America, and the Caribbean. S. haematobium is found in parts of Africa and the Middle East. Schistosoma japonicum is found in China, Indonesia, and the Philippines. Other human species are found in a more limited range in the Democratic Republic of the Congo (S. intercalatum), Central Africa (S. guineensis), and Laos and Cambodia.
Humans may become infected by S. haematobium during swimming in natural reservoirs of water containing ceriacs. The parasites inhabit stagnant water, such as lakes, ponds, and wetlands. Blood fluke infection can also occur through drinking unboiled water from natural reservoirs. Children and adolescents are most susceptible to infection.
Genitourinary schistosomiasis caused by Schistosoma haematobium is a serious, underestimated public health problem. It is endemic in 53 countries in Africa and the Middle East, affecting 200 million people worldwide. Adult worms live in the capillary plexus of the bladder and other parts of the urogenital tract, and eggs are excreted in the urine and sometimes found in the feces.

